Hyperpolarized and Inert Gas MRI. From Technology to by Mitchell S. Albert Ph.D., Francis T Hane Ph.D.

By Mitchell S. Albert Ph.D., Francis T Hane Ph.D.

Hyperpolarized and Inert fuel MRI: conception and functions in examine and Medicine is the 1st entire quantity released on HP fuel MRI. because the 1990’s, while HP fuel MRI was once invented via Dr. Albert and his colleagues, the HP gasoline MRI box has grown dramatically. The strategy has confirmed to be a useful gizmo for analysis, sickness staging, and treatment overview for obstructive lung illnesses, together with bronchial asthma, persistent obstructive pulmonary sickness (COPD), and cystic fibrosis.

HP gasoline MRI has additionally been constructed for sensible imaging of the mind and is shortly being built for molecular imaging, together with molecules linked to lung melanoma, breast melanoma, and Alzheimer’s illness. considering the continued progress of this box and the opportunity of destiny scientific functions, the ebook pulls jointly the main appropriate and state-of-the-art study to be had in HP fuel MRI into one resource.

  • Presents the main accomplished, proper, and exact info on HP fuel MRI
  • Co-edited through the co-inventor of HP fuel MRI, Dr. Albert, with bankruptcy authors who're the best specialists of their respective sub-disciplines
  • Serves as a origin of figuring out of HP gasoline MRI for researchers and clinicians keen on learn, know-how improvement, and scientific use with HP gasoline MRI
  • Covers all hyperpolarized gases, together with helium, the fuel with which nearly all of HP fuel MRI has been conducted

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Extra info for Hyperpolarized and Inert Gas MRI. From Technology to Application in Research and Medicine

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24950. [20] Wild JM, Paley MN, Viallon M, Schreiber WG, van Beek EJ, Griffiths PD. k-space filtering in 2D gradient-echo breath-hold hyperpolarized 3He MRI: spatial resolution and signal-to-noise ratio considerations. Magn Reson Med 2002;47(4):687À95. [21] Salerno M, Altes TA, Brookeman JR, de Lange EE, Mugler III JP. Dynamic spiral MRI of pulmonary gas flow using hyperpolarized 3He: preliminary studies in healthy and diseased lungs. Magn Reson Med 2001;46(4):667À77. [22] Wild JM, Paley MN, Kasuboski L, Swift A, Fichele S, Woodhouse N, et al.

88] Miller GW, Altes TA, Brookeman JR, de Lange EE, Mata JF, Mugler JP, III. Improving the quality of 3D hyperpolarized gas images using feedback-controlled flip-angle evolution. In: Proceedings of the 12th Annual Meeting of ISMRM. Kyoto, Japan; 2004. p. 1681. [89] Mugler JP, III. Optimization of gradient-echo sequences for hyperpolarized noble gas MRI. In: Proceedings of the 6th Annual Meeting of ISMRM. Sydney, Australia; 1998. p. 1904. [90] Deppe MH, Teh K, Parra-Robles J, Lee KJ, Wild JM. Slice profile effects in 2D slice-selective MRI of hyperpolarized nuclei.

To monitor the buildup of PXe via in situ NMR, single-shot “pulse-acquire” experiments suffice, and the ability to signal average is only needed if a calibration of the signal against water is required. Thus, a number of groups have constructed low-field spectrometers [84À87], though commercial systems (such as Magritek’s Kea and Aurora spectrometers) exist. , Ocean Optics HR4000). Nevertheless, these probes provide only part of the picture of what occurs within an SEOP cell during optical pumping.

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